In detail, the ICD score was positively correlated with the majority of immune cells, such as B cells, CD4 T cells, CD8 T cells, Macrophages, Monocytes, NK cells, Neutrophils, DC cells, Endothelial cells, and others, which were the primary effector cells and Antigen presentation cells in the anti-tumor immune response. This evidence concerns the gene CD8A and neoplasm.