DSG2 and neoplasm: We calculated the TSPAN1+ tumor EPCs score for each patient using the regression coefficients and expression levels of nine genes, as shown in the following formula: TSPAN1+ tumor EPCs score = (0.225314727) × (C4orf48 expression) + (0.207132307) × (CDC42EP5 expression) + (0.205498094) × (DSG2 expression) + (0.196215053) × (PTTG1IP expression) + (0.141686413) × (CA9 expression) + (0.13721923) × (ERO1A expression) -(0.257186496824633)×(ISG20 expression) - (0.454610734136572) × (CRIP1 expression) - (-0.0352359066640519) × (CD74 expression).