Similarly, a retrospective, observational study examining 87 lung cancer patients with CIP and 87 matched controls demonstrated that elevated levels of inflammatory cytokines IL-6 and IL-10, increased neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio, and elevated lactate dehydrogenase were significantly associated with CIP occurrence, while decreased absolute lymphocyte count and reduced albumin levels also correlated with pneumonitis development (37). This evidence concerns the gene IL6 and hereditary sensory and autonomic neuropathy.