NR4A3 and polycystic ovary syndrome: Experiments by Johansson et al. (57) further demonstrated this in a PCOS rat model: electroacupuncture countered DHT-induced changes by altering gene expression (decreased Tbc1d1 in soleus, increased Nr4a3 in mesenteric fat) and protein expression (increased pAS160/AS160, Nr4a3; decreased GLUT4).