This pattern is evident in the SHAP value plots, where higher expression values (indicated in red) are shifted toward the negative class (mutant) for BRAF and the positive class (wild-type) for ATRX and TP53. This is an interesting observation since BRAF is an oncogene and its associated genes appear more active in the mutated state, while ATRX and TP53 are tumour suppressors, whose functional networks are downregulated or disrupted in the presence of mutations. This evidence concerns the gene TP53 and neoplasm.