CLPP and cancer: Generally, isoTWAS exhibits higher CLPPs compared to TWAS, indicating a stronger likelihood of colocalization for isoform-eQTLs with GWAS loci (Fig. 3b), with the proportion of loci having isoform expression Quantitative Trait Loci (isoQTL) colocalizations with CLPP > 0.01 consistently higher across the 12 cancer outcomes (Supplemental Figure S23).