PLOD2 and nonpapillary renal cell carcinoma: Strikingly, RT-qPCR and Western blotting in both ccRCC cell lines revealed that β-catenin deficiency diminished hypoxia-induced DCLK1-L activation (Fig. 4H, I), while β-catenin restoration rescued PLOD2 depletion-suppressed DCLK1-L expression (Fig. 4J, K).