The substance P immunohistochemical expression optical density in the gastric mucosa of PC with gastritis was 2.3 as compared to 5.6 of healthy rats in the NC, while rats pretreated with FAM, AR-B 25 mg, and AR-B 50 mg demonstrated 2.6, 4.8, and 3.1, respectively. Here, TAC1 is linked to gastritis.