PAK6 and breast cancer: For example, YTHDF1 recognizes FTO-mediated m6A modification of ANGPTL4 and promotes translational enhancement of ANGPTL4 mRNA, which promotes breast cancer metastasis [46]; METTL3-mediated m6A modification stabilizes PAK6 mRNA through IGF2BP1 recognition and promotes cervical cancer growth and metastasis [47].