GSEA enrichment of KEGG Hippo signaling (Fig. 1G) and KEGG basal cell carcinoma (Fig. 1F) was driven by a strong enrichment for many genes related to wingless-related integration site (Wnt) signaling (e.g. WNT9A, WNT11, WNT5B, and WNT4) and bone morphogenetic protein (BMP) signaling (e.g. BMP2, BMP6, and BMPR1B) which have various profibrotic and antifibrotic functions in tissue fibrosis (24, 25, 26). The gene discussed is BMP6; the disease is basal cell carcinoma.