NFKB1 and periodontitis: <h4>Objectives</h4><i>Porphyromonas gingivalis</i> is a major contributing pathogen in periodontitis and triggers an inflammatory response that leads to tissue damage, primarily through the activation of proinflammatory cytokines such as nuclear factor kappa B (NF-κB) and tumor necrosis factor-α (TNF-α).