TRPV2 and cardiomyopathy: TRPV2 is still rather enigmatic, but recent studies have suggested its crucial role in several physiological functions including myocardial structure and function, innate immunity, neuronal outgrowth, sensory neuron mechanosensitivity, endocrine secretion, endometrial development, and thermogenesis in brown fat.2, 3, 4, 5, 6, 7, 8, 9, 10, 11 In terms of pathophysiology, TRPV2 seems to be important for the growth and invasiveness of various tumors, for the development of cardiomyopathy, and in the context of bacterial or virus infections.12, 13, 14, 15, 16, 17, 18