In our previously published human AML proteomics dataset of 44 patients (43), there were 2 patients with the DNMT3AR882C× NPM1c genotype who had a markedly higher abundance of both GRB2 and MAPK1 proteins than all the other 42 patients tested, despite an mRNA abundance more comparable to that in other AML samples (data not shown). This evidence concerns the gene GRB2 and acute myeloid leukemia.