POFUT1 and colorectal cancer: Similarly, observations were made in colorectal cancer, where POFUT1 knockdown led to a significantly higher proportion of apoptotic cells, with apoptosis rates increasing from 10.56% ± 1.33% in control SW620 cells to 17.23% ± 2.57% in POFUT1-silenced SW620 cells, and from 14.54% ± 1.78% to 25.91% ± 0.51% in control and POFUT1-silenced HCT116 cells, respectively [32].