Conversely, the outcome was worse in patients in whose lymphomas PD-L1+ B cell–rich RCN7 neighborhoods were located less than 800 pixels (267 μm) away from CD8+ T cell–rich RCN2 neighborhoods, independent of the IPI and COO (5-year PFS: 49.2% vs. 77.4%, P = 0.007; Fig. 4E–G; Supplementary Fig. S13B and S13C). The gene discussed is CD8A; the disease is lymphoma.