Survival was better in patients in whose lymphomas CD8+ T cell–rich RCN2 neighborhoods were situated less than 400 pixels (133 μm) away from the immune-poor RCN5 neighborhoods (5-year PFS: 87.8% vs. 65.7%, P = 0.039; Fig. 4C and G; Supplementary Fig. S13A). This evidence concerns the gene CD8A and lymphoma.