AKT1 and oral cavity squamous cell carcinoma: PER2‐silenced oral squamous cell carcinoma (OSCC) cells exhibited upregulated PI3K and phospho‐Akt(p‐Akt) expression, accompanied by enhanced activity of key glycolytic enzymes (HK2, PKM2, and LDHA), with resultant elevated glycolytic flux driving proliferation and suppressing apoptosis [66].