Then, we identified 11 potential mitosis-related downregulated hub genes, among which eight genes (KIF4A, BUB1B, NEK2, FBXO5, KIF11, CENPE, CCNA2, and NCAPG) showed good diagnostic properties of endometriosis and two genes (CCNA2, CENPE) were closely related to infertile endometriosis. Here, CCNA2 is linked to endometriosis.