We determined the cellular localisation of KPNA4 using DAB conjugated immunohistochemistry of KPNA4 performed on 22 post-mortem spinal cord tissue sections obtained from 5 control cases (2 females and 3 males; mean ± SD age 66.4 ± 9 years), 8 sporadic ALS cases (4 females and 4 males; mean ± SD age 61.4 ± 9 years) and 9 C9ALS cases (4 females and 5 males; mean ± SD age 73.7 ± 10.8 years). This evidence concerns the gene KPNA4 and amyotrophic lateral sclerosis.