EGFR and cancer: The KEGG analysis revealed several significant pathways, including pathways in cancer, the PI3K-Akt signaling pathway, proteoglycans in cancer, EGFR tyrosine kinase inhibitor resistance, the Rap1 signaling pathway, the Ras signaling pathway, the MAPK signaling pathway, microRNAs in cancer, the VEGF signaling pathway, and hepatocellular carcinoma (Figures 3A, B).