The examination uncovered that gene expression in IBD samples was significantly enriched in several key pathways, including reactome cellular response to hypoxia (Supplementary Figure S3B), TGF-beta receptor signaling (Supplementary Figure S3C), JAK-STAT signaling pathway (Supplementary Figure S3D), TH17 cell differentiation pathway (Supplementary Figure S3E), IBD signaling (Supplementary Figure S3F), and the intestinal immune network for IgA production (Supplementary Figure S3G), along with other biologically pertinent functions and signaling cascades. Here, SOAT1 is linked to inflammatory bowel disease.