Among otherfactors, its action may have to do with the activation of cell differentiation.Some studies suggest that, in differentiated neuroblastoma cells, the absenceof NGF induces apoptosis [31].Differentiation induction by retinoic acid [32, 33] is extensivelyutilized to treat low-risk neuroblastoma and as maintenance therapy for themore aggressive forms of the disease [34]. Here, NGF is linked to neuroblastoma.