As observed, AUC value of the model of FIT, KRAS and M3 integration was 0.864 in all patients, exhibiting no improvement over the AUC value compared to KRAS and M3 combination; AUC value of the model of FIT, KRAS and M3 integration was 0.878 in early CRC and 0.825 in advanced CRC (Figures 4A–C). Here, KRAS is linked to colorectal carcinoma.