Furthermore, it was found that in xenograft tumors derived from the two different sources, Bel-7402 and Hep-3B, the histochemistry score of CEP55 and Ki-67 in the shCEP55 group were significantly lower than those in the control group, further confirming the inhibitory effect of CEP55 knockdown on tumor cell proliferation (P ≤ 0.01) (Figures 11E, F). Here, MKI67 is linked to neoplasm.