A history of febrile seizures was associated with upregulation of basal phosphorylation at GluA1 Ser831 in six out of eight patient control regions and six out of seven patient epileptic lesions, which may correlate with the enhancement of basal excitatory synaptic strength in patients, reducing the threshold of hyperexcitability (Rakhade et al., 2012). Here, GRIA1 is linked to Febrile seizure (within the age range of 3 months to 6 years).