Mathematical models of AD frequently focus on the accumulation of harmful proteins such as τ and Aβ. Some employ sophisticated mathematical techniques to forecast the patterns of spread in brain geometries peculiar to individual patients (Corti, 2024), while others examine the interaction between various proteins and neuronal dynamics (Moravveji et al., 2024; Bertsch et al., 2020). The gene discussed is TBXT; the disease is Alzheimer disease.