All subjects were stratified by gender (female or male), age (<70 or ≥70 years), BMI (<25 or ≥25 kg/m2), smoking (yes or no), hypertension status (yes or no), diabetes status (non-diabetic, prediabetic, or diabetic), ALT (<22 or ≥22 U/L), AST (<20 or ≥20 U/L) and eGFR (<89 or ≥89 ml/min/1.73m2). The gene discussed is GPT; the disease is hypertensive disorder.