Behavior: Kinematics analysis at 1 and 1.5 ypi, increase in step duration and decreases in step length, limb length, and articulation range of motion in PSP-tau NHPs; Object retrieval task: ND on “easy” trials, completion time, or # of motor errors, but more cognitive errors on “hard” trials in PSP-tau NHPsNotes: *PSP-tau from the mesencephalon was selected due to higher in vitro seeding activity vs. frontal ctx.**One CTL brain sample had Braak II tauopathy and Thal I amyloid. The gene discussed is MAPT; the disease is tauopathy.