Furthermore, although our analysis revealed significant associations between key EV‐derived proteins (such as IL‐6, MCP‐1, and Oncostatin‐M) and AAA‐related inflammatory signalling pathways (e.g., AP‐1, GR, and chemokine signalling), the current findings remain at the correlative level due to the lack of direct functional validation. Here, CCL2 is linked to triple-A syndrome.