Although it is controversial that cisplatin and other chemotherapy drugs can induce an immune response of tumour cells experiments have found that STING recruits and activates downstream TBK1 kinase after the activation of intracellular DNA signal, and STING Ser366 is phosphorylated by TBK1 to initiate cascade signal transduction [24, 25]. The gene discussed is TBK1; the disease is neoplasm.