It mediates N(7)-methylguanine (m7G) formation as well as regulates mRNA translation.47 Abnormal METTL1 level was tightly linked to tumorigenesis as well as cancer progression in previous studies.48,49 Upregulation of METTL1 expression has recently been found to increase oncogenic activity and alter anticancer treatment resistance. Here, METTL1 is linked to cancer.