Notably, several individual variants previously reported in GWAS for eGFR were also replicated, including rs3850625 in CACNA1S (CKD, p-value = 2.37 × 10–2, OR = 0.235), rs34823813 in RNF123 (CKD, p-value = 2.43 × 10–2, OR = 7.452), and rs113956264 in RPL3L (CKD, p-value = 3.19 × 10–2, OR = 9.424). Here, RNF123 is linked to chronic kidney disease.