Among these, GP18, S0, GP5, G1, GP13, GP10, LB, GP4, and GP11 decreased, whereas GP32, GP19, GP34, S2, GP26, GP20, GP22, GP35, S3, and HB increased in prediabetes/T2D patients (Fig. 1; Supplementary Table 3). This evidence concerns the gene TNFSF4 and type 2 diabetes mellitus.