Studies have shown that in the presence of long non-coding RNA (lncRNA) MIR100HG, hnRNPA2B1 interacts with TCF7L2 in an m6A modification-dependent manner, maintaining the stability of TCF7L2 mRNA and thereby regulating the transcriptional activity of Wnt signal pathway in colorectal cancer [16]. The gene discussed is TCF7L2; the disease is colorectal cancer.