Quantification results indicated that in GIST-R9 and GIST430 cells, PLD2 knockdown reduced the protein levels of KIT (to 74% in GIST-R9 and 81% in GIST430), resulting in a decrease in pKITY703 (to 64% in GIST-R9 and 78% in GIST430) (Suppl. This evidence concerns the gene PLD2 and gastrointestinal stromal tumor.