SFRP1 and neoplasm: Analysis of v-SVZ VMRs at their syntenic human coordinates (“Methods”; Supplementary Data 4) revealed significant enrichment of astrocyte-specific VMRs hypomethylation in SFRP1-OE tumor cells (Fig. 7b), confirming that SFRP1-OE rewires tumor cell methylomes along with their transcriptomes and morphology.