No significant common variant associations were observed between NWD1 (±500 kb) and kidney calculus in the UKB WGS Consortium GWAS; however, a common synonymous variant, rs773852, is associated with kidney calculus in a Chinese Han population40 Our study demonstrates the potential of WGS in identifying non-protein-coding variant to phenotype associations. The gene discussed is NWD1; the disease is nephrolithiasis.