SDC4 and Bloom syndrome: We observed that Ackr3, Il1r1, Itgb1, Nrp2, Scarb1, Sdc4 and Tgfbr2 were all upregulated while Bmpr2 and Tgfbr3 were downregulated in BLM-treated compared to control gCap (Supplementary Fig. S5B).