For example, fibroblast growth factor 10 (FGF10) secreted by senescent mesenchymal cells induces multifocal prostate cancer,187 and the expression of fibroblast growth factor 19 by skeletal muscle cells can lead to hepatocellular carcinoma.188 (2) It contributes to tumor invasion and metastasis. This evidence concerns the gene FGF10 and prostate carcinoma.