In laboratory comparisons, patients in the HE group had significantly lower platelet counts, prolonged PT, activated partial thromboplastin time, and INR, higher serum levels of white blood count, ALT, AST, total bilirubin, direct bilirubin, γ-glutamyl transferase, ammonia, lactate, BUN, and creatinine, and lower levels of serum albumin, potassium, sodium, total cholesterol, high-density lipoprotein, and hemoglobin. The gene discussed is ALB; the disease is hereditary elliptocytosis.