Among these, TP53 and PIK3CA are IntOGen genes of both cohorts, while the roles of the other six genes, ACKR3, EIF1AX, FGFR3, LOX, RAC1, and GATA3, have also been highlighted in studies of both ovarian cancer and breast carcinoma [37–47]. The gene discussed is LOX; the disease is breast carcinoma.