POLR3A and infection: Overall, genes with type I (e.g., 5S rRNA) or type III (e.g., U6 RNA, 7SK RNA) promoters showed minimal or reduced Polr3A binding when comparing MHV68-infection to mock conditions, consistent with previous work (SI Appendix, Fig. S2 A and B) (45, 47, 48, 50, 51).