CPSF4 and infection: In addition to detecting CPSF30-occupied peaks at the transcription start site (TSS) and transcription end sites (TES) of Pol II-transcribed loci (SI Appendix, Fig. S3A), we observed infection-induced CPSF30 recruitment to Polr3A-occupied, highly expressed B2 SINE loci [n = 107, RPKM ≥ 5,000, from (47)] (Fig. 4 A and B).