INS and type 2 diabetes mellitus: Fifty-three BA (23 normal glucose tolerance, 11 impaired glucose tolerance and 19 type 2 diabetes) and 51 WE (23/13/15) men underwent a hyperglycaemic clamp and mixed-meal tolerance test to assess insulin secretion and beta cell function, a hyperinsulinaemic–euglycaemic clamp to measure insulin sensitivity and Dixon MRI to determine IPL.