CXCR3 and Sepsis: Notably, blocking CXCR3 was found associated with decreased organ lesions and mortality in a sepsis model.(5) Later in the disease process, the increase in regulatory T-cells (Tregs) in parallel with a change in the ILC profile might be relevant for lung recovery.(6) Although they represent rare populations, ILCs are fundamental to lung repair, as we have previously documented in patients with severe COVID-19, where recovery was linked with an increase in ILC1s.(7)