22 Riegger Riegger J J Rehm Rehm M M Büchele Büchele G G Brenner Brenner H H Günther Günther KP KP Rothenbacher Rothenbacher D D et al et al Serum Cartilage Oligomeric Matrix Protein in Late-Stage Osteoarthritis: Association with Clinical Features, Renal Function, and Cardiovascular Biomarkers Serum Cartilage Oligomeric Matrix Protein in Late-Stage Osteoarthritis: Association with Clinical Features, Renal Function, and Cardiovascular Biomarkers J Clin Med J Clin Med 2020 2020 9 9 1 1 268 268 10.3390/jcm9010268 10.3390/jcm9010268 31963737 31963737. This evidence concerns the gene COMP and osteoarthritis.