Patients in the highest LV mass quartile had higher levels of NT‐proBNP, indicating that not only patients with low LV mass show cardiac dysfunction, but also patients with higher LV mass are experiencing increased myocardial stress and reduced diastolic dysfunction as indicated by higher E/E′ mean values, possibly representing beginning dilated cardiomyopathy. Here, NPPB is linked to dilated cardiomyopathy.