PLXNA3 and alcohol dependence: Supplementary Table S1 presents estimates of SNP heritability (h2) (see Supplementary Results). Genetic correlations (rg) of alcohol consumption (39) with the steroid sex hormones and their binding proteins are presented in Table 1, and genetic correlations with alcohol dependence (40) are presented in Table 2. For convenient comparison, Tables 1, 2 also present the phenotypic associations of the same alcohol-use and sex hormone traits from a recently published study using data from the UK Biobank (18), adjacent to the estimated genetic correlations.