Comparisons of baseline data among the four groups revealed significant differences in body weight, race, white blood cell count, red blood cell distribution width, platelet count, albumin level, hemoglobin concentration, sodium, potassium, total calcium, chloride, glucose, pH, thrombin time, prothrombin time, international normalized ratio, alanine aminotransferase, aspartate aminotransferase, SOFA score, APACHE III score, SAPS II score, OASIS score, hypertension prevalence, heart failure incidence, myocardial infarction occurrence, and chronic kidney disease presence (P < 0.05). The gene discussed is F2; the disease is Hypertension.