The metabolic pathways significantly enriched in the MOD group compared to the NC group, in descending order of significance, included platinum drug resistance, thyroid hormone synthesis, drug metabolism-cytochrome P450, chemical carcinogenesis-DNA adducts, glutathione metabolism, various types of N-glycan biosynthesis, prostate cancer, metabolism of exogenous compounds by cytochrome P450, liver cancer, fluid shear stress and atherosclerosis, C-type lectin receptor signaling pathway, pancreatic secretion, and sphingolipid metabolism, among others (Figure 5A). Here, CLEC4D is linked to liver cancer.