CCDC88A and infection: Because the absolute numbers of macrophages and specifically, M2 macrophages—defined by established conventional markers CD68 and CD163, respectively (52–54)—were comparable between Citrobacter-infected control and GIV-KO intestinal tissues (Figure S3, A-D), we conclude that GIV deficiency impairs the healing functions of ColAMs without affecting macrophage trafficking or polarity-defining M2 markers at the site of infection.