Manches et al. did not find any difference in cord blood cytokines among healthy neonates in relation to maternal pre-pregnancy BMI, third-trimester maternal weight, or birth weight.(30) Serum IL-6 is correlated with infection, specifically chorioamnionitis, but not maternal diabetes.(31) Serum IL-10 has been found to be decreased in the serum of children with obesity and rats fed a high-fat diet.(32) Tissue-specific IL-10 levels are also reduced in neonatal mice born to dams fed a high-fat diet.(33) IL-10 is an anti-inflammatory cytokine that helps modulate the inflammatory response. This evidence concerns the gene IL10 and obesity due to melanocortin 4 receptor deficiency.